Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer’s disease, but the gene’s role in the disease has been unclear. Now, researchers funded by the National Institutes of Health have found that in mice, having the most risky variant of ApoE damages the blood vessels that feed the brain. The researchers found that the high-risk variant, ApoE4, triggers an inflammatory reaction that weakens the blood-brain barrier, a network of cells and other components that lines brain’s brain vessels…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/jvFxdWz7dAc/245509.php

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A hormone-depleting drug approved last year for the treatment of metastatic prostate cancer can help eliminate or nearly eliminate tumors in many patients with aggressive cancers that have yet to spread beyond the prostate, according to a clinical study to be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), June 1-5, in Chicago…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/GV60ZVES9h8/245540.php

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Genes play a greater role in forming character traits – such as self-control, decision making or sociability – than was previously thought, new research suggests. A study of more than 800 sets of twins found that genetics were more influential in shaping key traits than a person’s home environment and surroundings. Psychologists at the University of Edinburgh who carried out the study, say that genetically influenced characteristics could well be the key to how successful a person is in life…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/02gS0bF4FOY/245518.php

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A woman who is both over weight and pregnant faces double challenges, not least because many women who are not overweight struggle not to gain weight over the course of the nine month gestation period. Pregnant women who are overweight or obese can have serious health risks including high blood pressure, pre-eclampsia, diabetes and premature birth, but there is good news. A study published today on bmj.com shows that these risks can be mitigated by following a healthy calorie controlled diet over the course of the pregnancy…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/h6-MsYHV88o/245578.php

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Scientists are reporting development and testing of a new series of drugs that could finally stop the fox tapeworm – which causes a rare but life-threatening disease in humans – dead in its tracks. The report, which appears in ACS’ Journal of Medicinal Chemistry, shows that specific organometallic substances that help combat cancer are also the surprising best new hope for a treatment against tapeworm infection. Carsten Vock, Andrew Hemphill and colleagues explain that alveolar echinococcosis (AE) is a parasitic disease caused by the fox tapeworm Echinococcus multilocularis…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/L0AWGBLPFHA/245528.php

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The experimental drug ibrutinib (PCI-32765) shows great promise for the treatment of elderly patients with chronic lymphocytic leukemia (CLL), according to interim findings from a clinical trial. The phase I/II trial, co-led by researchers at the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and MD Anderson Cancer Center, indicates that the oral agent has few side effects and a high one-year survival rate in older patients…

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An article featured in BMJ reports on a ‘white paper’, which investigates as to how India and the UK can collaborate more closely in an equal partnership to improve both nations’ primary health care.The paper lists a number of opportunities based on India’s plans to achieve Universal Health Coverage, which requires the collaboration of the UK and India to benefit both nations by strengthening primary care in India and bringing expertise and innovations from India to improve care in the UK…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/CUf1tQUEiXs/245543.php

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An article featured in BMJ reports on a ‘white paper’, which investigates as to how India and the UK can collaborate more closely in an equal partnership to improve both nations’ primary health care.The paper lists a number of opportunities based on India’s plans to achieve Universal Health Coverage, which requires the collaboration of the UK and India to benefit both nations by strengthening primary care in India and bringing expertise and innovations from India to improve care in the UK…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/CUf1tQUEiXs/245543.php

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Source: http://cialis1227689.webs.com/apps/blog/show/15212125

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Targeted therapies have been studied for years, but recent laboratory research is providing robust clues about drugs that might work better in combination, particularly in treating cancers that have become resistant to therapy. That kind of information is behind a novel clinical trial at Georgetown Lombardi Comprehensive Cancer Center that combines cetuximab and lapatinib. Findings from this phase I study will be presented at the American Society of Clinical Oncology annual meeting in Chicago, June 1st through 5th…

Source: http://feedproxy.google.com/~r/mnt/healthnews/~3/byyCCVKGnJI/245513.php

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